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pantothenate biosynthesis

State Icon Reaction EC-Number Confidence maximal confidence score from EnzymeDetector
ATP + (R)-pantoate <=> H+ + ADP + (R)-4-phosphopantoate 2.7.1.169 pantoate kinase

(R)-pantoate + beta-Alanine + ATP <=> pantothenate + ADP + phosphate + H+ 6.3.2.44 pantoate---beta-alanine ligase (ADP-forming)

beta-Alanine + (R)-pantoate + ATP <=> H+ + pantothenate + diphosphate + AMP 6.3.2.1 pantoate---beta-alanine ligase (AMP-forming)

(R)-pantoate + NADP+ <=> H+ + ketopantoate + NADPH 1.1.1.169 2-dehydropantoate 2-reductase
1.1.1.86 ketol-acid reductoisomerase (NADP+)


(R)-4-phosphopantoate + beta-Alanine + ATP <=> (R)-4''-phosphopantothenate + AMP + diphosphate + H+ 6.3.2.36 4-phosphopantoate---beta-alanine ligase

5,10-methylenetetrahydrofolate + 2-oxoisovalerate + H2O <=> ketopantoate + tetrahydrofolate 2.1.2.11 3-methyl-2-oxobutanoate hydroxymethyltransferase

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